Endocrine Abstracts

Introduction and importance: Pseudo-Cushing’s syndrome (PCS) encompasses a spectrum of medical conditions, both physiological and non-physiological, that replicate the clinical features of Cushing’s syndrome (CS). In PCS, there is a presence of mild biochemical hypercortisolaemia, which is carefully regulated by physiological feedback hormonal control mechanisms. Physiological conditions contributing to PCS include factors like pregnancy surgical or emotional stress,...

Introduction and importance: Ovarian Sertoli-Leydig cell tumors (SLCT) are rare sex cord-stromal tumors, representing less than 0.5% of all ovarian malignancies. Typically diagnosed at a young age, with 75% of patients having an average onset age of less than 30, these tumors often present a management challenge due to their early detection in young women. The primary dilemma lies in striking the right balance between implementing an effective treatment to prevent recurrences ...

Introduction and importance: Insulinoma is a rare pancreatic neuroendocrine tumor characterized by hypersecretion of insulin, leading to neuroglycopenia symptoms and heightened sympathoadrenal activity. Incidence ranges from 1 to 4 cases per million inhabitants annually, with a predilection for females in their fourth or fifth decade. Despite its rarity, underdiagnosis is suggested by autopsy studies, revealing higher prevalence. Clinical manifestations often mimic other condi...